Sinus node dysfunction (SND)

A disorder of the sinoatrial node that fails to pace the heart reliably.

Key ECG features

  • ✓Sinus rate or pauses inappropriate for the patient's state
  • •Inappropriate sinus bradycardia
  • •Prolonged sinus pauses or arrest
  • ±Junctional or ventricular escape beats rescuing the pauses
  • ±Alternating bradycardia and supraventricular tachycardia

✓ required · • typical · ± may be present

ECG characteristics

Inappropriate sinus bradycardia, prolonged sinus pauses or arrest, and often alternating bradycardia and supraventricular tachycardia (sick sinus syndrome), with junctional or ventricular escape beats rescuing the long pauses.

This illustration is schematic. Dashed line is a normal rhythm. The grid is not drawn to scale.

Common causes

Degenerative disease of the sinus node, classically in older small-breed female dogs - Miniature Schnauzers, West Highland White Terriers, Cocker Spaniels and Dachshunds are over-represented. It is essentially a canine diagnosis and the equivalent is rare in cats.

Why it matters

Pauses that persist despite atropine and correlate with weakness or syncope support the diagnosis. It is a leading indication for pacemaker implantation.

Differentiate from

  • Sinus bradycardiaSinus bradycardia is a finding. This is the diagnosis behind a bradycardia or pauses that persist despite atropine and correlate with weakness or syncope.
  • Sinus pause & arrestPauses are the finding; sinus node dysfunction is the underlying disorder when they are long, frequent, or symptomatic.

Example tracings

Dog · Mixed breed · 10 years · Female (Recorded with Beecardia)Open in full viewer ↗
Sick sinus syndrome - a junctional rhythm with a long 1.3 s sinus arrest and non-conducted P waves, explaining the syncope.
Dog · Male (Recorded with Beecardia)Open in full viewer ↗
Sinus node dysfunction with frequent sinus pauses and junctional escape beats and a delayed (~8 min) response to atropine.
Dog · Chihuahua · 18 years · Female (Recorded with Beecardia)Open in full viewer ↗
An underlying sinus rhythm with frequent pauses up to ~4 s interrupted by ventricular escape beats, suggestive of sinus node dysfunction.